Mounjaro vs Wegovy: what's the difference?
Both Mounjaro and Wegovy are prescription-only weight loss treatments. This page explains how they compare – final decisions are always made by a clinician after reviewing your medical history.
Frequently Asked Questions
Can I switch from Wegovy to Mounjaro or vice versa?
Switching between GLP-1 treatments is possible but should only be done under clinical guidance. Your prescriber will consider your response to the current treatment, any side effects, and whether switching might offer benefits. There may be a transition period and dose adjustments required.
Is Mounjaro stronger than Wegovy?
Mounjaro (tirzepatide) works on two receptors (GLP-1 and GIP) compared to Wegovy's single GLP-1 receptor. Clinical trials have shown greater average weight loss with Mounjaro, but 'stronger' doesn't mean 'better for you' - the right choice depends on your individual health profile, tolerability, and other factors your prescriber will consider.
What if one weight loss treatment doesn't work for me?
If one treatment does not produce the expected response or causes intolerable side effects, a clinician can review progress and discuss whether dose adjustment, switching or additional support is appropriate.
Aans Memon
Prescribing Pharmacist
MPharm, IP
Aans specialises in chronic disease management and patient counselling, with particular expertise in weight management medications.
Last reviewed: 11 January 2026