Treclin

It combines two complementary actions. Tretinoin (a topical retinoid) normalises how keratinocytes shed inside the follicle — reducing microcomedone formation. Clindamycin (a topical antibiotic) kills Cutibacterium acnes bacteria and reduces inflammation. Used once daily, the combination addresses both comedonal and inflammatory acne.

Clinical response is typically assessed at 8–12 weeks. In weeks 2–4 you may notice a temporary flare as the retinoid clears microcomedones faster — this is expected and usually settles with continued use and a bland moisturiser.

Duac is clindamycin + BPO (antibiotic-led). Epiduo is adapalene + BPO (retinoid + BPO). Treclin is tretinoin + clindamycin (retinoid + antibiotic). Your pharmacist picks the combination that matches your lesion type, tolerance, and antibiotic-stewardship considerations.

A pea-sized amount spread thinly across the affected areas, once a night. More is not better — over-application increases irritation without improving efficacy.

No. Retinol is a cosmetic precursor that skin converts slowly into retinoic acid. Tretinoin IS retinoic acid — the active form — and it's a prescription medicine, much more potent than cosmetic retinol, with evidence of effect on acne at licensed strengths.

Acne is a long-term condition. Recurrence is common when any topical treatment stops. UK guidance recommends continuing for several months after clearance and then stepping down under pharmacist review — typically to tretinoin alone or to a BPO-based combination for maintenance.

Because Treclin contains a topical antibiotic (clindamycin), UK guidance keeps antibiotic-containing topical therapy to the minimum effective duration — typically up to 12 weeks — to reduce the risk of driving antibiotic resistance in skin flora.

Dryness, peeling, redness, and mild stinging — most common in the first 4 weeks. A temporary 'retinoid purge' (short-term flare) in weeks 2–4 is also expected.

No. Topical retinoids are avoided in pregnancy and when planning pregnancy. If you become pregnant during treatment, stop and inform your pharmacist or GP. Systemic absorption is low but the precaution is standard.

No — not if you have a history of ulcerative colitis, Crohn's disease, or antibiotic-associated colitis. Although rare with topical clindamycin, this is a standard precaution. Disclose your history at consultation.

Yes — daily broad-spectrum SPF 30+ is essential. Tretinoin increases UV sensitivity and acne pigmentation worsens without sun protection.

Stop treatment and seek urgent medical advice. Severe, persistent, or bloody diarrhoea during or shortly after topical clindamycin is rare but reported and requires clinical assessment.

Reduce to every other night for 1–2 weeks and use a bland moisturiser. If irritation persists, stop and message the pharmacist team — some people do better on a lower-strength regimen or a different combination.

In discreet, unbranded packaging with a generic sender name, sent by DPD tracked delivery.

A 30g tube typically lasts around 4–6 weeks with once-daily facial application at a pea-sized dose. We ship on a monthly cadence and adjust if your response is slower.

No — store at room temperature, away from direct sunlight.

Any time. Pause, skip, or cancel from your Caremacy account with no notice period or fees.

A qualified prescriber reviews every request. Treclin is prescription-only and suitability is verified before prescribing; treatment is declined where it is not clinically appropriate, including pregnancy or some IBD histories.

Yes. Use secure messaging in your Caremacy dashboard. For severe diarrhoea or any suspected severe allergic reaction, stop treatment and seek urgent medical advice.

UK guidance limits topical-antibiotic courses to around 12 weeks. At review, the pharmacist will typically step you down to tretinoin alone or swap to a BPO-based maintenance regimen to limit antibiotic resistance.

Only with your explicit consent. We encourage it for continuity — particularly given the topical antibiotic component.